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Expression of Ac-PK2 protein from AcMNPV improved the progeny virus production via regulation of energy metabolism and protein synthesis

Baculovirus encoded PK2 protein can increase viral fitness through inhibition of the eIF2α family kinases activity. Previous studies indicated that the virus might take over the control of cellular machinery post-infection, which would impose a high metabolic burden to infected insect cells. Here we...

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Detalles Bibliográficos
Autores principales: Wei, Lili, Liang, Aihua, Fu, Yuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085523/
https://www.ncbi.nlm.nih.gov/pubmed/35548732
http://dx.doi.org/10.1039/c8ra05172k