A new sensitive UPLC-MS/MS method for the determination of cucurbitacin B in rat plasma: application to an absolute bioavailability study

Cucurbitacin B (CuB) is a highly oxygenated tetracyclic triterpene, and a Biopharmaceutics Classification System (BCS) class IV drug used for the treatment of persistent hepatitis, chronic hepatitis, and primary liver cancer. Nevertheless, CuB has low solubility and low permeability, and is present...

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Detalles Bibliográficos
Autores principales: Xiao, Ya, Zhao, Qiang, Wu, Qian, Chang, Jinhua, Xue, Hefei, Liu, Cuizhe, Liu, Xigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085573/
https://www.ncbi.nlm.nih.gov/pubmed/35548771
http://dx.doi.org/10.1039/c8ra05941a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085573/
https://www.ncbi.nlm.nih.gov/pubmed/35548771
http://dx.doi.org/10.1039/c8ra05941a

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