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On the direct use of CO(2) in multicomponent reactions: introducing the Passerini four component reaction

We introduce a novel isocyanide-based multicomponent reaction, the Passerini four component reaction (P-4CR), by replacing the carboxylic acid component of a conventional Passerini three component reaction (P-3CR) with an alcohol and CO(2). Key to this approach is the use of a switchable solvent sys...

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Detalles Bibliográficos
Autores principales: Onwukamike, Kelechukwu Nnabuike, Grelier, Stéphane, Grau, Etienne, Cramail, Henri, Meier, Michael A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085615/
https://www.ncbi.nlm.nih.gov/pubmed/35548239
http://dx.doi.org/10.1039/c8ra07150k