Synthesis of novel genistein amino acid derivatives and investigation on their interactions with bovine serum albumin by spectroscopy and molecular docking

Genistein amino acid derivatives 4a–4d were synthesized and evaluated for their cytotoxic activities against MCF-7, Hela, MGC-803 and HCT-116 cell lines by MTT assays in vitro. The results revealed that compounds 4a–4d showed better activity than the parent compound genistein. Particularly, compound...

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Detalles Bibliográficos
Autores principales: Long, Xiaokang, Zeng, Yao-Fu, Liu, Yunmei, Liu, Ying, Li, Tangluo, Liao, Lanqing, Guo, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085648/
https://www.ncbi.nlm.nih.gov/pubmed/35548766
http://dx.doi.org/10.1039/c8ra06691d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085648/
https://www.ncbi.nlm.nih.gov/pubmed/35548766
http://dx.doi.org/10.1039/c8ra06691d

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