Detecting Validated Intracellular ROS Generation with (18)F-dihydroethidine-Based PET

PURPOSE: To determine the sensitivity of the (18)F-radiolabelled dihydroethidine analogue ([(18)F]DHE) to ROS in a validated ex vivo model of tissue oxidative stress. PROCEDURES: The sensitivity of [(18)F]DHE to various ROS-generating systems was first established in vitro. Then, isolated rat hearts...

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Detalles Bibliográficos
Autores principales: Waters, Edward C. T., Baark, Friedrich, Yu, Zilin, Mota, Filipa, Eykyn, Thomas R., Yan, Ran, Southworth, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Brief Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085669/
https://www.ncbi.nlm.nih.gov/pubmed/34820762
http://dx.doi.org/10.1007/s11307-021-01683-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085669/
https://www.ncbi.nlm.nih.gov/pubmed/34820762
http://dx.doi.org/10.1007/s11307-021-01683-0

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