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Towards Optimized Bioavailability of (99m)Tc-Labeled Barbiturates for Non-invasive Imaging of Matrix Metalloproteinase Activity

INTRODUCTION: Dysregulated activity of matrix metalloproteinases (MMPs) drives a variety of pathophysiological conditions. Non-invasive imaging of MMP activity in vivo promises diagnostic and prognostic value. However, current targeting strategies by small molecules are typically limited with respec...

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Detalles Bibliográficos
Autores principales: Honold, Lisa, Austrup, Melanie, Faust, Andreas, Konken, Christian Paul, Schwegmann, Katrin, Zinnhardt, Bastian, Daniliuc, Constantin Gabriel, Haufe, Günter, Schäfers, Michael, Kopka, Klaus, Hermann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085681/
https://www.ncbi.nlm.nih.gov/pubmed/34750717
http://dx.doi.org/10.1007/s11307-021-01668-z