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Determination of a distinguished interferon gamma epitope recognized by monoclonal antibody relating to autoantibody associated immunodeficiency

Anti-interferon gamma autoantibodies (anti-IFN-γ autoAbs) neutralize the IFN-γ-mediated functions, contributing to immunodeficiency. A particular autoAb in patient serum had been previously demonstrated to recognize the same determinant on IFN-γ as the neutralizing anti-IFN-γ monoclonal antibody clo...

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Detalles Bibliográficos
Autores principales: Yasamut, Umpa, Wisitponchai, Tanchanok, Lee, Vannajan Sanghiran, Yamabhai, Montarop, Rangnoi, Kuntalee, Thongkum, Weeraya, Chupradit, Koollawat, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085737/
https://www.ncbi.nlm.nih.gov/pubmed/35534543
http://dx.doi.org/10.1038/s41598-022-11774-9