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Identification of oleoylethanolamide as an endogenous ligand for HIF-3α

Hypoxia-inducible factors (HIFs) are α/β heterodimeric transcription factors modulating cellular responses to the low oxygen condition. Among three HIF-α isoforms, HIF-3α is the least studied to date. Here we show that oleoylethanolamide (OEA), a physiological lipid known to regulate food intake and...

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Detalles Bibliográficos
Autores principales: Diao, Xiaotong, Ye, Fei, Zhang, Meina, Ren, Xintong, Tian, Xiaoxu, Lu, Jingping, Sun, Xiangnan, Hou, Zeng, Chen, Xiaoyu, Li, Fengwei, Zhuang, Jingjing, Ding, Hong, Peng, Chao, Rastinejad, Fraydoon, Luo, Cheng, Wu, Dalei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085743/
https://www.ncbi.nlm.nih.gov/pubmed/35534502
http://dx.doi.org/10.1038/s41467-022-30338-z