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Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies

Antibiotic tolerance, or the ability of bacteria to survive antibiotic treatment in the absence of genetic resistance, has been linked to chronic and recurrent infections. Tolerant cells are often characterized by a low metabolic state, against which most clinically used antibiotics are ineffective....

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Detalles Bibliográficos
Autores principales: Zheng, Erica J., Andrews, Ian W., Grote, Alexandra T., Manson, Abigail L., Alcantar, Miguel A., Earl, Ashlee M., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085803/
https://www.ncbi.nlm.nih.gov/pubmed/35534481
http://dx.doi.org/10.1038/s41467-022-30272-0