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Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches

Epitranscriptomic features, such as single-base RNA editing, are sources of transcript diversity in cancer, but little is understood in terms of their spatial context in the tumour microenvironment. Here, we introduce spatial-histopathological examination-linked epitranscriptomics converged to trans...

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Detalles Bibliográficos
Autores principales: Lee, Amos C., Lee, Yongju, Choi, Ahyoun, Lee, Han-Byoel, Shin, Kyoungseob, Lee, Hyunho, Kim, Ji Young, Ryu, Han Suk, Kim, Hoe Suk, Ryu, Seung Yeon, Lee, Sangeun, Cheun, Jong-Ho, Yoo, Duck Kyun, Lee, Sumin, Choi, Hansol, Ryu, Taehoon, Yeom, Huiran, Kim, Namphil, Noh, Jinsung, Lee, Yonghee, Kim, Inyoung, Bae, Sangwook, Kim, Jinhyun, Lee, Wooseok, Kim, Okju, Jung, Yushin, Kim, Changhoe, Song, Seo Woo, Choi, Yeongjae, Chung, Junho, Kim, Byung Gee, Han, Wonshik, Kwon, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085828/
https://www.ncbi.nlm.nih.gov/pubmed/35534484
http://dx.doi.org/10.1038/s41467-022-30299-3