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Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy

Lung cancer is the leading cause of cancer-related death worldwide despite the success of therapies targeting oncogenic drivers and immune-checkpoint inhibitors. Although metabolic enzymes offer additional targets for therapy, the precise metabolic proteome of lung adenocarcinomas is unknown, hamper...

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Detalles Bibliográficos
Autores principales: Torresano, Laura, Santacatterina, Fulvio, Domínguez-Zorita, Sonia, Nuevo-Tapioles, Cristina, Núñez-Salgado, Alfonso, Esparza-Moltó, Pau B., González-Llorente, Lucía, Romero-Carramiñana, Inés, Núñez de Arenas, Cristina, Sánchez-Garrido, Brenda, Nájera, Laura, Salas, Clara, Provencio, Mariano, Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085865/
https://www.ncbi.nlm.nih.gov/pubmed/35534478
http://dx.doi.org/10.1038/s41389-022-00400-y