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Reaching alignment-profile-based accuracy in predicting protein secondary and tertiary structural properties without alignment
Protein language models have emerged as an alternative to multiple sequence alignment for enriching sequence information and improving downstream prediction tasks such as biophysical, structural, and functional properties. Here we show that a method called SPOT-1D-LM combines traditional one-hot enc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085874/ https://www.ncbi.nlm.nih.gov/pubmed/35534620 http://dx.doi.org/10.1038/s41598-022-11684-w |