Interaction mechanism of olaparib binding to human serum albumin investigated with NMR relaxation data and computational methods

The interaction mechanism between olaparib (OLA) and human serum albumin (HSA) has been investigated using experimental and computational techniques. An NMR relaxation approach based on the analysis of proton selective and non-selective spin–lattice relaxation rates at different temperatures can pro...

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Detalles Bibliográficos
Autores principales: Zhai, Yuanming, Deng, Pengchi, Wang, Xiaoyan, Zhang, Chunchun, Gan, Ruixue, Gan, Na, Sun, Qiaomei, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085917/
https://www.ncbi.nlm.nih.gov/pubmed/35548207
http://dx.doi.org/10.1039/c8ra05330h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085917/
https://www.ncbi.nlm.nih.gov/pubmed/35548207
http://dx.doi.org/10.1039/c8ra05330h

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