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Mitochondrial ROS in Slc4a11 KO Corneal Endothelial Cells Lead to ER Stress
Recent studies from Slc4a11 ( −/− ) mice have identified glutamine-induced mitochondrial dysfunction as a significant contributor toward oxidative stress, impaired lysosomal function, aberrant autophagy, and cell death in this Congenital Hereditary Endothelial Dystrophy (CHED) model. Because lysosom...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086159/ https://www.ncbi.nlm.nih.gov/pubmed/35557943 http://dx.doi.org/10.3389/fcell.2022.878395 |