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Berberine Attenuates Cell Motility via Inhibiting Inflammation-Mediated Lysyl Hydroxylase-2 and Glycolysis

Lysyl hydroxylase-2 (LH2) involves in the hydroxylation of telopeptide lysine residues during collagen deposition. Recent studies indicate that interleukin (IL)-6 generated by the chronic inflammation disease may trigger the LH2 expression to accelerate cell motility. Berberine is the alkaloid deriv...

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Detalles Bibliográficos
Autores principales: Du, Yishan, Khan, Muhammad, Fang, Nana, Ma, Fang, Du, Hongzhi, Tan, Zhenya, Wang, Hua, Yin, Shi, Wei, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086160/
https://www.ncbi.nlm.nih.gov/pubmed/35559258
http://dx.doi.org/10.3389/fphar.2022.856777