Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways

A highly efficient metal free approach for the oxidation of primary and secondary amines to their corresponding aldehydes and ketones using PhI(OAc)(2) in combination with a catalytic amount of TEMPO as an oxidizing agent is described. This protocol is rapid and provides diverse products under milde...

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Detalles Bibliográficos
Autores principales: Bansode, Ajay H., Suryavanshi, Gurunath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086218/
https://www.ncbi.nlm.nih.gov/pubmed/35547530
http://dx.doi.org/10.1039/c8ra07451h
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author Bansode, Ajay H.
Suryavanshi, Gurunath
author_facet Bansode, Ajay H.
Suryavanshi, Gurunath
author_sort Bansode, Ajay H.
collection PubMed
description A highly efficient metal free approach for the oxidation of primary and secondary amines to their corresponding aldehydes and ketones using PhI(OAc)(2) in combination with a catalytic amount of TEMPO as an oxidizing agent is described. This protocol is rapid and provides diverse products under milder reaction conditions in excellent yields. In addition, the mechanistic study is well demonstrated by spectroscopic methods.
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spelling pubmed-90862182022-05-10 Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways Bansode, Ajay H. Suryavanshi, Gurunath RSC Adv Chemistry A highly efficient metal free approach for the oxidation of primary and secondary amines to their corresponding aldehydes and ketones using PhI(OAc)(2) in combination with a catalytic amount of TEMPO as an oxidizing agent is described. This protocol is rapid and provides diverse products under milder reaction conditions in excellent yields. In addition, the mechanistic study is well demonstrated by spectroscopic methods. The Royal Society of Chemistry 2018-09-14 /pmc/articles/PMC9086218/ /pubmed/35547530 http://dx.doi.org/10.1039/c8ra07451h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Bansode, Ajay H.
Suryavanshi, Gurunath
Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title_full Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title_fullStr Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title_full_unstemmed Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title_short Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways
title_sort metal-free hypervalent iodine/tempo mediated oxidation of amines and mechanistic insight into the reaction pathways
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086218/
https://www.ncbi.nlm.nih.gov/pubmed/35547530
http://dx.doi.org/10.1039/c8ra07451h
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AT suryavanshigurunath metalfreehypervalentiodinetempomediatedoxidationofaminesandmechanisticinsightintothereactionpathways

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