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Preparation of chiral 3-oxocycloalkanecarbonitrile and its derivatives by crystallization-induced diastereomer transformation of ketals with chiral 1,2-diphenylethane-1,2-diol

Chiral 3-oxocycloalkanecarbonitriles were prepared by fractional crystallization and crystallization-induced diastereomer transformation (CIDT) of diastereomeric ketals with (1R,2R)-1,2-diphenylethane-1,2-diol. Investigation of the crystal structures by X-ray diffraction analysis revealed that the d...

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Detalles Bibliográficos
Autores principales: Yamashita, Yohei, Maki, Daisuke, Sakurai, Shiho, Fuse, Takumi, Matsumoto, Shoji, Akazome, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086373/
https://www.ncbi.nlm.nih.gov/pubmed/35547706
http://dx.doi.org/10.1039/c8ra06611f