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Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na(+) Channel and the NaCl Cotransporter

Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na(+) reabsorption via the epithelial Na(+) channel (ENaC) and the NaCl cotransporter (NCC). The majority of PA patients have normal plasma K(+) levels, but a subset of case...

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Detalles Bibliográficos
Autores principales: Kristensen, Mathias, Fenton, Robert A., Poulsen, Søren B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086401/
https://www.ncbi.nlm.nih.gov/pubmed/35557966
http://dx.doi.org/10.3389/fphys.2022.800055