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Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na(+) Channel and the NaCl Cotransporter
Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na(+) reabsorption via the epithelial Na(+) channel (ENaC) and the NaCl cotransporter (NCC). The majority of PA patients have normal plasma K(+) levels, but a subset of case...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086401/ https://www.ncbi.nlm.nih.gov/pubmed/35557966 http://dx.doi.org/10.3389/fphys.2022.800055 |