Asymmetric vinylogous aldol addition of alkylidene oxindoles on trifluoromethyl-α,β-unsaturated ketones

A novel vinylogous aldol addition of alkylidene oxindole with 1-trifluoromethyl-3-alkylidene-propan-2-ones is presented. The reaction, catalyzed by a bifunctional tertiary amine, provides an efficient application of the vinylogous reactivity of oxindoles for the preparation of enantioenriched triflu...

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Detalles Bibliográficos
Autores principales: Crotti, Simone, Belletti, Giada, Di Iorio, Nicola, Marotta, Emanuela, Mazzanti, Andrea, Righi, Paolo, Bencivenni, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086480/
https://www.ncbi.nlm.nih.gov/pubmed/35548158
http://dx.doi.org/10.1039/c8ra06615a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086480/
https://www.ncbi.nlm.nih.gov/pubmed/35548158
http://dx.doi.org/10.1039/c8ra06615a

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