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Asymmetric vinylogous aldol addition of alkylidene oxindoles on trifluoromethyl-α,β-unsaturated ketones

A novel vinylogous aldol addition of alkylidene oxindole with 1-trifluoromethyl-3-alkylidene-propan-2-ones is presented. The reaction, catalyzed by a bifunctional tertiary amine, provides an efficient application of the vinylogous reactivity of oxindoles for the preparation of enantioenriched triflu...

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Detalles Bibliográficos
Autores principales:	Crotti, Simone, Belletti, Giada, Di Iorio, Nicola, Marotta, Emanuela, Mazzanti, Andrea, Righi, Paolo, Bencivenni, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086480/ https://www.ncbi.nlm.nih.gov/pubmed/35548158 http://dx.doi.org/10.1039/c8ra06615a

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