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Do P2Y12 receptor inhibitors prescribed poststroke modify the risk of cognitive disorder or dementia? Protocol for a target trial using multiple national Swedish registries

INTRODUCTION: The target of a class of antiplatelet medicines, P2Y12R inhibitors, exists both on platelets and on brain immune cells (microglia). This protocol aims to describe a causal (based on a counterfactual model) approach for analysing whether P2Y12R inhibitors prescribed for secondary preven...

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Detalles Bibliográficos
Autores principales: Hinwood, Madeleine, Nyberg, Jenny, Leigh, Lucy, Gustavsson, Sara, Attia, John, Oldmeadow, Christopher, Ilicic, Marina, Linden, Thomas, Åberg, N David, Levi, Chris, Spratt, Neil, Carey, Leeanne M, Pollack, Michael, Johnson, Sarah J, Kuhn, Georg Hans, Walker, Frederick R, Nilsson, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086614/
https://www.ncbi.nlm.nih.gov/pubmed/35534077
http://dx.doi.org/10.1136/bmjopen-2021-058244