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One-pot facile and mild construction of densely functionalized pyrimidines in water via consecutive C–C and C–S bonds formation
Fused pyrimidines composed of alternating heteroatoms and a pyrimidine moiety were synthesized efficiently using readily available starting material 4-hydroxycoumarin, aromatic aldehydes, and urea/thiourea at room temperature. Acid, metal salts, and surfactants were screened for their influence on c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086688/ https://www.ncbi.nlm.nih.gov/pubmed/35548808 http://dx.doi.org/10.1039/c8ra04363a |