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One-pot facile and mild construction of densely functionalized pyrimidines in water via consecutive C–C and C–S bonds formation

Fused pyrimidines composed of alternating heteroatoms and a pyrimidine moiety were synthesized efficiently using readily available starting material 4-hydroxycoumarin, aromatic aldehydes, and urea/thiourea at room temperature. Acid, metal salts, and surfactants were screened for their influence on c...

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Detalles Bibliográficos
Autores principales: Sahu, Pramod K., Sahu, Praveen K., Kaurav, Manvendra S., Messali, Mouslim, Almutairi, Saud M., Sahu, Puran L., Agarwal, Dau D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086688/
https://www.ncbi.nlm.nih.gov/pubmed/35548808
http://dx.doi.org/10.1039/c8ra04363a