Modified Adenosines Sensitize Glioblastoma Cells to Temozolomide by Affecting DNA Methyltransferases

Glioblastoma (GBM) is the most common and lethal primary malignant brain tumor, and due to its unique features, its management is certainly one of the most challenging ones among all cancers. N6-isopentenyladenosine (IPA) and its analog N6-benzyladenosine (N6-BA) are modified nucleosides endowed wit...

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Detalles Bibliográficos
Autores principales: Proto, Maria Chiara, Fiore, Donatella, Piscopo, Chiara, Laezza, Chiara, Bifulco, Maurizio, Gazzerro, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086827/
https://www.ncbi.nlm.nih.gov/pubmed/35559231
http://dx.doi.org/10.3389/fphar.2022.815646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086827/
https://www.ncbi.nlm.nih.gov/pubmed/35559231
http://dx.doi.org/10.3389/fphar.2022.815646

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