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Electrooxidative tricyclic 6–7–6 fused-system domino assembly to allocolchicines by a removable radical strategy

Natural allocolchicine and analogues derived thereof a tricyclic 6–7–6-system have been found as key scaffold of various biologically relevant molecules. However, the direct preparation of the allocolchicine motif remains difficult to date. Herein, we report on an electrooxidative radical cyclizatio...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Ma, Chanchan, Cai, Zhenzhi, Struwe, Julia, Chen, Shengjie, Xu, Jinming, Li, Shiyin, Zeng, Wangyu, Ackermann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086860/
https://www.ncbi.nlm.nih.gov/pubmed/35694222
http://dx.doi.org/10.1039/d2gc00684g