Screening of cytochrome P450 3A4 inhibitors via in silico and in vitro approaches

Cytochrome P450 3A4 (CYP3A4) is an important member of the CYP family and responsible for metabolizing a broad range of drugs. Potential drug–drug interactions (DDIs) caused by CYP3A4 inhibitors could lead to increasing risk of side-effects/toxicity or decreasing effectiveness. The evaluation of CYP...

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Detalles Bibliográficos
Autores principales: Pang, Xiaocong, Zhang, Baoyue, Mu, Guangyan, Xia, Jie, Xiang, Qian, Zhao, Xia, Liu, Ailin, Du, Guanhua, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086869/
https://www.ncbi.nlm.nih.gov/pubmed/35547066
http://dx.doi.org/10.1039/c8ra06311g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086869/
https://www.ncbi.nlm.nih.gov/pubmed/35547066
http://dx.doi.org/10.1039/c8ra06311g

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