cGAS Restricts PRRSV Replication by Sensing the mtDNA to Increase the cGAMP Activity

Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that causes great economic losses globally to the swine industry. Innate immune RNA receptors mainly sense it during infection. As a DNA sensor, cyclic GMP-AMP synthase (cGAS) plays an important role in sensing cytosolic DNA...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Na, Li, Li-Wei, Gao, Fei, Jiang, Yi-Feng, Yuan, Wan-Zhe, Li, Guo-Xin, Yu, Ling-Xue, Zhou, Yan-Jun, Tong, Guang-Zhi, Zhao, Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086901/
https://www.ncbi.nlm.nih.gov/pubmed/35558078
http://dx.doi.org/10.3389/fimmu.2022.887054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086901/
https://www.ncbi.nlm.nih.gov/pubmed/35558078
http://dx.doi.org/10.3389/fimmu.2022.887054

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