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An efficient and atom-economical route to N-aryl amino alcohols from primary amines

In this paper we reported a novel method for generation of N-aryl amino alcohols from N,N-disubstituted picolinamides through reduction/ring-opening reaction with NaBH(4). The N,N-disubstituted picolinamides can be easily obtained from primary amines after convenient condensation with picolinic acid...

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Detalles Bibliográficos
Autores principales: Xiao, Zhen, Li, Juanjuan, Yue, Qiang, Zhang, Qian, Li, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086943/
https://www.ncbi.nlm.nih.gov/pubmed/35548644
http://dx.doi.org/10.1039/c8ra07355d