Cargando…

Advanced palladium free approach to the synthesis of substituted alkene oxindoles via aluminum-promoted Knoevenagel reaction

A synthetic route for the synthesis of C24, as well as for the design of focused libraries of direct AMPK activators was developed based on a convergent strategy. The proposed scheme corresponds to the current trends in C–H bond functionalization. The use of aluminum isopropoxide for the Knoevenagel...

Descripción completa

Detalles Bibliográficos
Autores principales: Novikova, Daria S., Grigoreva, Tatyana A., Zolotarev, Andrey A., Garabadzhiu, Alexander V., Tribulovich, Vyacheslav G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9086994/
https://www.ncbi.nlm.nih.gov/pubmed/35548634
http://dx.doi.org/10.1039/c8ra07576j