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Accessing local structural disruption of Bid protein during thermal denaturation by absorption-mode ESR spectroscopy

Bid is a requisite protein that connects death receptors to the initiation of mitochondrial-dependent apoptosis. Its structure was determined more than a decade ago, but its structure–function relationship remains largely unexplored. Here we investigate the thermostability of Bid protein and explore...

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Detalles Bibliográficos
Autores principales: Hung, Chien-Lun, Lin, Yu-Ying, Chang, Hsin-Ho, Chiang, Yun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087001/
https://www.ncbi.nlm.nih.gov/pubmed/35548640
http://dx.doi.org/10.1039/c8ra06740f