Sec-O-Glucosylhamaudol Inhibits RANKL-Induced Osteoclastogenesis by Repressing 5-LO and AKT/GSK3β Signaling

Sec-O-glucosylhamaudol (SOG), an active flavonoid compound derived from the root of Saposhnikovia divaricata (Turcz. ex Ledeb.) Schischk., exhibits analgesic, anti-inflammatory, and high 5-lipoxygenase (5-LO) inhibitory effects. However, its effect on osteoclastogenesis was unclear. We demonstrated...

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Detalles Bibliográficos
Autores principales: Cao, Jinjin, Zhou, Ming-Xue, Chen, Xinyan, Sun, Menglu, Wei, Congmin, Peng, Qisheng, Cheng, Zhou, Sun, Wanchun, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087042/
https://www.ncbi.nlm.nih.gov/pubmed/35558084
http://dx.doi.org/10.3389/fimmu.2022.880988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087042/
https://www.ncbi.nlm.nih.gov/pubmed/35558084
http://dx.doi.org/10.3389/fimmu.2022.880988

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