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Development of flow cytometry‐based assays to assess the ability of antibodies to bind to SARS‐CoV‐2‐infected and spike‐transfected cells and mediate NK cell degranulation

Since the beginning of the SARS‐CoV‐2 pandemic, antibody responses and antibody effector functions targeting SARS‐CoV‐2‐infected cells have been understudied. Consequently, the role of these types of antibodies in SARS‐CoV‐2 disease (COVID‐19) and immunity is still undetermined. To provide tools to...

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Detalles Bibliográficos
Autores principales: Mielke, Dieter, Stanfield‐Oakley, Sherry, Jha, Shalini, Keyes, Taylor, Zalaquett, Adam, Dunn, Brooke, Rodgers, Nicole, Oguin, Thomas, Sempowski, Greg D., Binder, Raquel A., Gray, Gregory C., Karuna, Shelly, Corey, Lawrence, Hural, John, Tomaras, Georgia D., Pollara, Justin, Ferrari, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087172/
https://www.ncbi.nlm.nih.gov/pubmed/35301794
http://dx.doi.org/10.1002/cyto.a.24552