Chemoenzymatic Synthesis of the Most Pleasant Stereoisomer of Jessemal

[Image: see text] We describe the asymmetric synthesis of the most pleasant enantiomer of Jessemal fragrance. The key steps are (i) the one-pot reduction of an α-chloro-tetrasubstituted cyclohexenone to give the chlorohydrin, catalyzed by two stereoselective redox enzymes (an ene-reductase and an al...

Descripción completa

Detalles Bibliográficos
Autores principales: Venturi, Silvia, Trajkovic, Milos, Colombo, Danilo, Brenna, Elisabetta, Fraaije, Marco W., Gatti, Francesco G., Macchi, Piero, Zamboni, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087343/
https://www.ncbi.nlm.nih.gov/pubmed/35442680
http://dx.doi.org/10.1021/acs.joc.2c00427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087343/
https://www.ncbi.nlm.nih.gov/pubmed/35442680
http://dx.doi.org/10.1021/acs.joc.2c00427

Ejemplares similares