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Study of the Addition Mechanism of 1H-Indazole and Its 4-, 5-, 6-, and 7-Nitro Derivatives to Formaldehyde in Aqueous Hydrochloric Acid Solutions

[Image: see text] The reaction of NH-indazoles with formaldehyde in aqueous hydrochloric acid has been experimentally studied by solution and solid-state nuclear magnetic resonance (NMR) and crystallography. The mechanism of the formation of N(1)-CH(2)OH derivatives was determined. For the first tim...

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Detalles Bibliográficos
Autores principales: Alkorta, Ibon, Claramunt, Rosa M., Elguero, José, Gutiérrez-Puebla, Enrique, Monge, M. Ángeles, Reviriego, Felipe, Roussel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087356/
https://www.ncbi.nlm.nih.gov/pubmed/35405072
http://dx.doi.org/10.1021/acs.joc.2c00154