Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity

A significant number of COVID‐19 patients were shown to have neutralizing antibodies (NAB) against IFN; however, NAB specificity, fluctuation over time, associations with biochemical and hematological parameters, and IFN gene expression are not well characterized. Binding antibodies (BAB) to IFN‐α/‐...

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Detalles Bibliográficos
Autores principales: Frasca, Federica, Scordio, Mirko, Santinelli, Letizia, Gabriele, Lucia, Gandini, Orietta, Criniti, Anna, Pierangeli, Alessandra, Angeloni, Antonio, Mastroianni, Claudio M., d'Ettorre, Gabriella, Viscidi, Raphael P., Antonelli, Guido, Scagnolari, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Immunity to infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087404/
https://www.ncbi.nlm.nih.gov/pubmed/35419822
http://dx.doi.org/10.1002/eji.202249824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087404/
https://www.ncbi.nlm.nih.gov/pubmed/35419822
http://dx.doi.org/10.1002/eji.202249824

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