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CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis

OBJECTIVE: To observe expression of CD38, a key modulator of nicotinamide dinucleotide (NAD+) metabolism in mice with knee osteoarthritis, and protective effect of CD38 inhibition during the osteoarthritis (OA) development. METHOD: The destabilization of the medial meniscus (DMM) model was performed...

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Detalles Bibliográficos
Autores principales: Ma, Jin‐jin, Ying, Jun, Wang, Jin‐yu, Xu, Tao‐tao, Xia, Han‐ting, Jin, Hong‐ting, Xiao, Lu‐wei, Shang, Wen‐jun, Wang, Wei‐qian, Feng, Jian‐yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087467/
https://www.ncbi.nlm.nih.gov/pubmed/35441488
http://dx.doi.org/10.1111/os.13258