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A Genomic Signature Reflecting Fibroblast Infiltration Into Gastric Cancer Is Associated With Prognosis and Treatment Outcomes of Immune Checkpoint Inhibitors

Background: The immunotherapy efficacy in gastric cancer (GC) is limited. Cancer-associated fibroblasts (CAFs) induce primary resistance to immunotherapy. However, CAF infiltration in tumors is difficult to evaluate due to the lack of validated and standardized quantified methods. This study aimed t...

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Detalles Bibliográficos
Autores principales: Lu, Yi, Li, Dan, Cao, Yixin, Ying, Leqian, Tao, Qing, Xiong, Fen, Hu, Zhangmin, Yang, Yufei, Qiao, Xuehan, Peng, Chen, Zhu, Dongqin, Wang, Deqiang, Li, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087633/
https://www.ncbi.nlm.nih.gov/pubmed/35557959
http://dx.doi.org/10.3389/fcell.2022.862294