Cargando…

A Genomic Signature Reflecting Fibroblast Infiltration Into Gastric Cancer Is Associated With Prognosis and Treatment Outcomes of Immune Checkpoint Inhibitors

Background: The immunotherapy efficacy in gastric cancer (GC) is limited. Cancer-associated fibroblasts (CAFs) induce primary resistance to immunotherapy. However, CAF infiltration in tumors is difficult to evaluate due to the lack of validated and standardized quantified methods. This study aimed t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yi, Li, Dan, Cao, Yixin, Ying, Leqian, Tao, Qing, Xiong, Fen, Hu, Zhangmin, Yang, Yufei, Qiao, Xuehan, Peng, Chen, Zhu, Dongqin, Wang, Deqiang, Li, Xiaoqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087633/ https://www.ncbi.nlm.nih.gov/pubmed/35557959 http://dx.doi.org/10.3389/fcell.2022.862294

Ejemplares similares

Lipid metabolism reprogramming in tumor-associated macrophages and implications for therapy
por: Qiao, Xuehan, et al.
Publicado: (2023)

The Pyroptosis-Related Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Gastric Cancer
por: Shao, Wei, et al.
Publicado: (2021)

Immune Cell Infiltration as Signatures for the Diagnosis and Prognosis of Malignant Gynecological Tumors
por: Liu, Qi-Fang, et al.
Publicado: (2021)

Glutamine Metabolism Scoring Predicts Prognosis and Therapeutic Resistance in Hepatocellular Carcinoma
por: Ying, Leqian, et al.
Publicado: (2021)

The Prognosis and Immune Checkpoint Blockade Efficacy Prediction of Tumor-Infiltrating Immune Cells in Lung Cancer
por: Liu, Xiangzheng, et al.
Publicado: (2021)

Pyroptosis-Related Gene Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Glioma
por: Zhang, Yulian, et al.
Publicado: (2022)

Application of Immune Infiltration Signature and Machine Learning Model in the Differential Diagnosis and Prognosis of Bone-Related Malignancies
por: Li, Guo-Qi, et al.
Publicado: (2021)

Identification of lung adenocarcinoma subtypes and predictive signature for prognosis, immune features, and immunotherapy based on immune checkpoint genes
por: Hua, Linbin, et al.
Publicado: (2023)

Prognosis and Immunotherapy Significances of a Cancer-Associated Fibroblasts-Related Gene Signature in Gliomas
por: Chen, Zhimin, et al.
Publicado: (2021)

Identification of an Metabolic Related Risk Signature Predicts Prognosis in Cervical Cancer and Correlates With Immune Infiltration
por: Shang, Chunliang, et al.
Publicado: (2021)

ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
por: Yang, Yufei, et al.
Publicado: (2022)

Identification and Validation of Pyroptosis-Related Gene Signature to Predict Prognosis and Reveal Immune Infiltration in Hepatocellular Carcinoma
por: Fu, Xiao-Wei, et al.
Publicado: (2021)

Identification of a Gene Signature for Renal Cell Carcinoma–Associated Fibroblasts Mediating Cancer Progression and Affecting Prognosis
por: Liu, Bitian, et al.
Publicado: (2021)

Identification of an m6A Regulators-Mediated Prognosis Signature For Survival Prediction and Its Relevance to Immune Infiltration in Melanoma
por: Wu, Liuxing, et al.
Publicado: (2021)

Identification of novel lactate metabolism signatures and molecular subtypes for prognosis in hepatocellular carcinoma
por: Guan, Qiutong, et al.
Publicado: (2022)

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal Melanoma
por: Sun, Yifang, et al.
Publicado: (2021)

A Ferroptosis-Related lncRNAs Signature Predicts Prognosis and Therapeutic Response of Gastric Cancer
por: Xiao, Shilang, et al.
Publicado: (2021)

Transcriptomic and Metabolomic Profiling in Helicobacter pylori–Induced Gastric Cancer Identified Prognosis- and Immunotherapy-Relevant Gene Signatures
por: Liu, Duanrui, et al.
Publicado: (2021)

Association of aging-related genes with prognosis and immune infiltration in pancreatic adenocarcinoma
por: Xue, Shengbai, et al.
Publicado: (2022)

Ferroptosis-related gene signatures in neuroblastoma associated with prognosis
por: Chen, Yiru, et al.
Publicado: (2022)

Comprehensive Analysis of the Glycolysis-Related Gene Prognostic Signature and Immune Infiltration in Endometrial Cancer
por: Yang, Xiao, et al.
Publicado: (2022)

Pyroptosis-Related Signature and Tumor Microenvironment Infiltration Characterization in Head and Neck Squamous Cell Carcinoma
por: Wu, Zeng-Hong, et al.
Publicado: (2022)

Glycolysis Define Two Prognostic Subgroups of Lung Adenocarcinoma With Different Mutation Characteristics and Immune Infiltration Signatures
por: Huo, Chen, et al.
Publicado: (2021)

Identification of an Immune-Related LncRNA Signature in Gastric Cancer to Predict Survival and Response to Immune Checkpoint Inhibitors
por: Ding, Zuoyou, et al.
Publicado: (2021)

The hypoxia-related signature predicts prognosis, pyroptosis and drug sensitivity of osteosarcoma
por: Hu, Lin, et al.
Publicado: (2022)

Construction of Two Alternative Polyadenylation Signatures to Predict the Prognosis of Sarcoma Patients
por: Hu, Chuan, et al.
Publicado: (2021)

Immune Cell Infiltration Landscape of Ovarian Cancer to Identify Prognosis and Immunotherapy-Related Genes to Aid Immunotherapy
por: Li, Xiushen, et al.
Publicado: (2021)

Two Similar Signatures for Predicting the Prognosis and Immunotherapy Efficacy of Stomach Adenocarcinoma Patients
por: Yue, Taohua, et al.
Publicado: (2021)

SUMOylation patterns and signature characterize the tumor microenvironment and predict prognosis in lung adenocarcinoma
por: Chen, Zhike, et al.
Publicado: (2023)

Development and Validation of a Hypoxia-Associated Prognostic Signature Related to Osteosarcoma Metastasis and Immune Infiltration
por: Fu, Yucheng, et al.
Publicado: (2021)

Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma
por: Fan, Lei, et al.
Publicado: (2021)

An Iron Metabolism-Related Gene Signature for the Prognosis of Colon Cancer
por: Yuan, Jing, et al.
Publicado: (2022)

Pyroptosis-Related lncRNAs for Predicting the Prognosis and Identifying Immune Microenvironment Infiltration in Breast Cancer Lung Metastasis
por: Liu, Li, et al.
Publicado: (2022)

Integrative Analysis of MUC4 to Prognosis and Immune Infiltration in Pan-Cancer: Friend or Foe?
por: Gao, Xiao-Peng, et al.
Publicado: (2021)

Upregulated ENC1 predicts unfavorable prognosis and correlates with immune infiltration in endometrial cancer
por: He, Lingling, et al.
Publicado: (2022)

TNF Family–Based Signature Predicts Prognosis, Tumor Microenvironment, and Molecular Subtypes in Bladder Carcinoma
por: Li, Huihuang, et al.
Publicado: (2022)

Identification of an Autophagy-Related Risk Signature Correlates With Immunophenotype and Predicts Immune Checkpoint Blockade Efficacy of Neuroblastoma
por: Kang, Wenjuan, et al.
Publicado: (2021)

Identification and Validation of an 11-Ferroptosis Related Gene Signature and Its Correlation With Immune Checkpoint Molecules in Glioma
por: Chen, Zhuohui, et al.
Publicado: (2021)

A Novel DNA Repair Gene Signature for Immune Checkpoint Inhibitor-Based Therapy in Gastric Cancer
por: Yuan, Binbin, et al.
Publicado: (2022)

Comprehensive Analysis of the Expression and Prognosis for ITGBs: Identification of ITGB5 as a Biomarker of Poor Prognosis and Correlated with Immune Infiltrates in Gastric Cancer
por: Liu, Dongliang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hc5gv5klkplcvhha4qfdrs1frl