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BDNF Val66Met Polymorphism Reduces the Fatigue-Like Effects of 5-Fluorouracil on Voluntary Wheel-Running Activity in Mice

Fatigue is a persistent and debilitating symptom following cancer treatments such as chemotherapy. Recent clinical studies have suggested a common single-nucleotide polymorphism of brain-derived neurotrophic factor (BDNF), Val66Met (rs6265), may be related to the severity of fatigue following cancer...

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Detalles Bibliográficos
Autores principales: Wolff, Brian S., Allen, Hannah R., Feng, Li Rebekah, Saligan, Leorey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087735/
https://www.ncbi.nlm.nih.gov/pubmed/35558437
http://dx.doi.org/10.3389/fnbeh.2022.880969