Development of a high-throughput and sensitive assay of fusion genes in lung cancer by array-based MALDI-TOFMS

ALK (anaplastic lymphoma kinase gene), ROS1 (ros proto-oncogene 1) and RET (ret proto-oncogene) fusions are oncogenic drivers in non-small cell lung cancer (NSCLC). Methods like fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) are highly sensitive but subjectively analyzed, l...

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Detalles Bibliográficos
Autores principales: Wu, Han-Tao, Li, Kun, Wang, Gang, Yang, Xue-Xi, Zhu, Anna, Xu, Xu-Ping, Li, Ming, Wu, Ying-Song, Liu, Tian-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087866/
https://www.ncbi.nlm.nih.gov/pubmed/35548167
http://dx.doi.org/10.1039/c8ra05165h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087866/
https://www.ncbi.nlm.nih.gov/pubmed/35548167
http://dx.doi.org/10.1039/c8ra05165h

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