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Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases

Objective: Background incidence rates are routinely used in safety studies to evaluate an association of an exposure and outcome. Systematic research on sensitivity of rates to the choice of the study parameters is lacking. Materials and Methods: We used 12 data sources to systematically examine the...

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Detalles Bibliográficos
Autores principales: Ostropolets, Anna, Li, Xintong, Makadia, Rupa, Rao, Gowtham, Rijnbeek, Peter R., Duarte-Salles, Talita, Sena, Anthony G., Shaoibi, Azza, Suchard, Marc A., Ryan, Patrick B., Prieto-Alhambra, Daniel, Hripcsak, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087898/
https://www.ncbi.nlm.nih.gov/pubmed/35559254
http://dx.doi.org/10.3389/fphar.2022.814198