Reliability analysis of exonic-breakpoint fusions identified by DNA sequencing for predicting the efficacy of targeted therapy in non-small cell lung cancer

BACKGROUND: Diverse genomic breakpoints of fusions that localize to intronic, exonic, or intergenic regions have been identified by DNA next-generation sequencing (NGS), but the role of exonic breakpoints remains elusive. We investigated whether exonic-breakpoint fusions could predict matched target...

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Detalles Bibliográficos
Autores principales: Li, Weihua, Wan, Rui, Guo, Lei, Chang, Geyun, Jiang, Dong, Meng, Lin, Ying, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087946/
https://www.ncbi.nlm.nih.gov/pubmed/35534835
http://dx.doi.org/10.1186/s12916-022-02362-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087946/
https://www.ncbi.nlm.nih.gov/pubmed/35534835
http://dx.doi.org/10.1186/s12916-022-02362-9

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