Cargando…

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome

miR-486 is a muscle-enriched microRNA, or “myomiR,” that has reduced expression correlated with Duchenne muscular dystrophy (DMD). To determine the function of miR-486 in normal and dystrophin-deficient muscles and elucidate miR-486 target transcripts in skeletal muscle, we characterized mir-486 kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Samani, Adrienne, Hightower, Rylie M, Reid, Andrea L, English, Katherine G, Lopez, Michael A, Doyle, J Scott, Conklin, Michael J, Schneider, David A, Bamman, Marcas M, Widrick, Jeffrey J, Crossman, David K, Xie, Min, Jee, David, Lai, Eric C, Alexander, Matthew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087951/
https://www.ncbi.nlm.nih.gov/pubmed/35512829
http://dx.doi.org/10.26508/lsa.202101215