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miR-486 is essential for muscle function and suppresses a dystrophic transcriptome
miR-486 is a muscle-enriched microRNA, or “myomiR,” that has reduced expression correlated with Duchenne muscular dystrophy (DMD). To determine the function of miR-486 in normal and dystrophin-deficient muscles and elucidate miR-486 target transcripts in skeletal muscle, we characterized mir-486 kno...
Autores principales: | Samani, Adrienne, Hightower, Rylie M, Reid, Andrea L, English, Katherine G, Lopez, Michael A, Doyle, J Scott, Conklin, Michael J, Schneider, David A, Bamman, Marcas M, Widrick, Jeffrey J, Crossman, David K, Xie, Min, Jee, David, Lai, Eric C, Alexander, Matthew S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087951/ https://www.ncbi.nlm.nih.gov/pubmed/35512829 http://dx.doi.org/10.26508/lsa.202101215 |
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