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Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice

BACKGROUND: The zinc finger domain containing transcription factor Myt1l is tightly associated with neuronal identity and is the only transcription factor known that is both neuron-specific and expressed in all neuronal subtypes. We identified Myt1l as a powerful reprogramming factor that, in combin...

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Detalles Bibliográficos
Autores principales: Wöhr, Markus, Fong, Wendy M., Janas, Justyna A., Mall, Moritz, Thome, Christian, Vangipuram, Madhuri, Meng, Lingjun, Südhof, Thomas C., Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087967/
https://www.ncbi.nlm.nih.gov/pubmed/35538503
http://dx.doi.org/10.1186/s13229-022-00497-3