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Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice
BACKGROUND: The zinc finger domain containing transcription factor Myt1l is tightly associated with neuronal identity and is the only transcription factor known that is both neuron-specific and expressed in all neuronal subtypes. We identified Myt1l as a powerful reprogramming factor that, in combin...
Autores principales: | Wöhr, Markus, Fong, Wendy M., Janas, Justyna A., Mall, Moritz, Thome, Christian, Vangipuram, Madhuri, Meng, Lingjun, Südhof, Thomas C., Wernig, Marius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087967/ https://www.ncbi.nlm.nih.gov/pubmed/35538503 http://dx.doi.org/10.1186/s13229-022-00497-3 |
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