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Highly efficient soluble expression, purification and characterization of recombinant Aβ42 from Escherichia coli

Aggregation of amyloid-β protein (Aβ) is hypothesized to be a seminal neuropathological event in Alzheimer's disease (AD). Recombinant expression and purification of Aβ represents a common basis for investigating the molecular mechanisms of amyloid formation and toxicity. Herein, we report a no...

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Detalles Bibliográficos
Autores principales: Jia, Longgang, Wang, Wenjuan, Shang, Jinzhao, Zhao, Wenping, Wei, Wei, Wang, Ying, Li, Li, Lu, Fuping, Liu, Fufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087987/
https://www.ncbi.nlm.nih.gov/pubmed/35546794
http://dx.doi.org/10.1039/c8ra00042e