Locked and Loaded: Mechanisms Regulating Natural Killer Cell Lytic Granule Biogenesis and Release

NK cell-mediated cytotoxicity is a critical element of our immune system required for protection from microbial infections and cancer. NK cells bind to and eliminate infected or cancerous cells via direct secretion of cytotoxic molecules toward the bound target cells. In this review, we summarize th...

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Detalles Bibliográficos
Autores principales: Ham, Hyoungjun, Medlyn, Michael, Billadeau, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088006/
https://www.ncbi.nlm.nih.gov/pubmed/35558071
http://dx.doi.org/10.3389/fimmu.2022.871106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088006/
https://www.ncbi.nlm.nih.gov/pubmed/35558071
http://dx.doi.org/10.3389/fimmu.2022.871106

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