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Locked and Loaded: Mechanisms Regulating Natural Killer Cell Lytic Granule Biogenesis and Release
NK cell-mediated cytotoxicity is a critical element of our immune system required for protection from microbial infections and cancer. NK cells bind to and eliminate infected or cancerous cells via direct secretion of cytotoxic molecules toward the bound target cells. In this review, we summarize th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088006/ https://www.ncbi.nlm.nih.gov/pubmed/35558071 http://dx.doi.org/10.3389/fimmu.2022.871106 |