Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity

[Image: see text] A selection of compounds from a proprietary library, based on chemical diversity and various biological activities, was evaluated as potential inhibitors of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a phenotypic-based screening assay. A compound based on a...

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Detalles Bibliográficos
Autores principales: Nizi, Maria Giulia, Persoons, Leentje, Corona, Angela, Felicetti, Tommaso, Cernicchi, Giada, Massari, Serena, Manfroni, Giuseppe, Vangeel, Laura, Barreca, Maria Letizia, Esposito, Francesca, Jochmans, Dirk, Milia, Jessica, Cecchetti, Violetta, Schols, Dominique, Neyts, Johan, Tramontano, Enzo, Sabatini, Stefano, De Jonghe, Steven, Tabarrini, Oriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088073/
https://www.ncbi.nlm.nih.gov/pubmed/35571875
http://dx.doi.org/10.1021/acsmedchemlett.2c00123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088073/
https://www.ncbi.nlm.nih.gov/pubmed/35571875
http://dx.doi.org/10.1021/acsmedchemlett.2c00123

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