Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer

BACKGROUND: Although gemcitabine has been considered as the first-line drug for advanced pancreatic cancer (PC), development of resistance to gemcitabine severely limits the effectiveness of this chemotherapy, and the underlying mechanism of gemcitabine resistance remains unclear. Various factors, s...

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Detalles Bibliográficos
Autores principales: Gu, Jianyou, Huang, Wenjie, Wang, Xianxing, Zhang, Junfeng, Tao, Tian, Zheng, Yao, Liu, Songsong, Yang, Jiali, Chen, Zhe-Sheng, Cai, Chao-Yun, Li, Jinsui, Wang, Huaizhi, Fan, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088115/
https://www.ncbi.nlm.nih.gov/pubmed/35538494
http://dx.doi.org/10.1186/s12943-022-01587-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088115/
https://www.ncbi.nlm.nih.gov/pubmed/35538494
http://dx.doi.org/10.1186/s12943-022-01587-9

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